Pour prouver que même pour les plantes, le clonage ne représente pas une identitée ...
Transgenic Res 2001 Jun;10(3):223-36
Related Articles, Links
Influence of plant development and environment on transgene expression in potato
andconsequences for insect resistance.
Down RE, Ford L, Bedford SJ, Gatehouse LN, Newell C, Gatehouse JA, Gatehouse AM.
Department of Agricultural and Environmental Science, University of Newcastle, Newcastle upon Tvne, UK.a.m.r.gathouse@newcastle.ac.uk
Clonal replicates of different transformed potato plants expressing transgene
constructs containing the constitutiveCauliflower Mosaic Virus (CaMV) 35S promoter,
and sequences encoding the plant defensive proteins snowdrop lectin (Galanthus
nivalis agglutinin; GNA), and bean chitinase (BCH) were propagated in tissue
culture. Plants were grown tomaturity, at first under controlled environmental
conditions, and later in the glasshouse. For a given transgene product,protein
accumulation was found to vary between the different lines of clonal replicates
(where each line was derived from a single primary transformant plant), as expected.
However, variability was also found to exist within each line of clonal replicates,
comparable to the variation of mean
expression levels observed between the different clonal lines. Levels of
GNA, accumulated in different parts of a transgenic
potato plant, also showed variation but to a lesser extent than
plant-plant variation in expression. With the majority of
the clonal lines investigated, accumulation of the transgene
product was found to increase as the potato plant
developed, with maximum levels found in mature plants. The variation in
accumulation of GNA among transgenic plants within a line
of clonal replicates was exploited to demonstrate that the
enhanced resistance towards larvae of the tomato moth,
Lacanobia oleracea L., caused by expression of this protein in
potato, was directly correlated with the level of GNA
present in the plants, and that conditions under which the plants
were grown affect the levels of GNA expression and
subsequent levels of insect resistance.
PMID: 11437279 [PubMed - indexed for MEDLINE]
« Quand la première fécondation in vitro a eu lieu en 1978, j'ai compris que ça n'était plus qu'une question de temps avant le clonage d'animaux et aussi d'humains [...] Il faut toutefois se souvenir que le clonage n'est pas comparable à la bombe atomique. La seule personne qui sera affectée par le clonage sera le clone lui-même » J. Watson Libération 14 mars 1997. Bien sûr une société où un enfant serait cloné n'affecterait pas que l'enfant, mais bien toute la société.
Clonage thérapeutique
Sur le clonage "therapeutique" :
http://www.ccne-ethique.fr/francais/avis/a_067.html et http://www.ccne-ethique.fr/francais/avis/a_067p2.html
(en piece jointe a l'envoi suivant a mettre en archives) :
Sur la question du clonage thérapeutique, en revanche, les opinions divergent. Si tous s'accordent à estimer que cette question soulève des problèmes éthiques très difficiles, les membres du CCNE sont partagés, selon leur vision du monde et du futur, entre les deux positions qui ont été présentées, une majorité se dégageant en faveur de la seconde de ces positions cest-à-dire celle qui est favorable à l'autorisation encadrée du clonage dit thérapeutique.